Dietary emamectin benzoate alters the gill and spleen histoarchitecture of monosex Oreochromis niloticus fry

Jasmine Singha; Thangapalam Jawahar Abraham

doi:10.17017/j.fish.1001

Jasmine Singha Department of Aquatic Animal Health, West Bengal University of Animal and Fishery Sciences, Chakgaria, Kolkata 700094, India
Thangapalam Jawahar Abraham Department of Aquatic Animal Health, West Bengal University of Animal and Fishery Sciences, Chakgaria, Kolkata 700094, India https://orcid.org/0000-0003-0581-1307

DOI: https://doi.org/10.17017/j.fish.1001

Keywords: all-male tilapia, antiparasitic veterinary drugs, ectoparasites, histopathology, tropical aquaculture

Abstract

Oral administration of the antiparasitic veterinary drug emamectin benzoate is recommended to control infectious ectoparasites, whose biosafety and effect on vital organs are unknown in several fish species. This study evaluated the influence of dietary emamectin benzoate on the histopathology of hitherto understudied organs, such as gills and spleen of all-male Oreochromis niloticus fry at the recommended dose of 50 µg and an overdose of 500 µg kg body weight^–1 day^–1 for 7 days. The fry recorded dose-dependent discrepancies in feed intake, survival and biomass. Histologically, noticeable pathological changes in the gill and spleen tissues were documented in both groups. The pathological alterations in the fry fed the recommended dose and increased severity in the overdosed groups indicated the toxic nature of emamectin benzoate and signified exercising caution during its application in tropical aquaculture.

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